Single- and multiorgan transplantations for the treatment of terminal cardiac, pulmonary, hepatic and renal diseases gain therapeutic importance and transplantation research using mammalian models of isolated perfused organs resembles a major field for the improvement of transplantation techniques. We established a new method of multiple organ harvesting from slaughterhouse pigs which may be us...

One of the most important issues in area of health and hygiene is location-allocation of organ harvesting centers and transplant centers according to coordination between supply and demand. In this paper, a mathematical model is presented for location-allocation of organ harvesting centers and transplant centers. The proposed model does not only minimize the present value of the total system co...

OBJECTIVE Radial artery pedicle tissue cooling during harvesting is one of the major causes of vasospasm. We aimed to compare the effects of the pedicle rewarming method, normothermic organ bath, and one of the most preferred topical antispasmodic agents, verapamil-nitroglycerin solution alone or in combination on the blood flow of radial artery. METHODS Consecutively randomized patients (n=8...

A rapid technique for multiple organ harvesting is described which allows removal of all the major organs within 30 to 60 minutes after beginning the donor operation. No preliminary dissection of the liver or kidneys is required or necessary since these organs are cooled by infusion of cold solutions in situ and with subsequent rapid dissection in a bloodless field. The incidence of well functi...

BACKGROUND [18F]UCB-H was developed as a novel radiotracer with a high affinity for synaptic vesicle protein 2A, the binding site for the antiepileptic levetiracetam. The objectives of this study were to evaluate the radiation dosimetry of [18F]UCB-H in a preclinical trial and to determine the maximum injectable dose according to guidelines for human biomedical research. The radiation dosimetry...

The real goal of donor heart assessment is not to estimate the functional status of the heart just before the organ harvesting but rather to predict the performance of the transplanted graft after weaning from the extracorporeal circulation and in the postoperative period. For that, hemodynamic and myocardial assessment during organ harvesting is important but is only one of several aspects. On...

Occasionally brain-dead organ donors go into cardiac arrest before reaching the operating theater. In such cases, the needed resuscitation of the potential donor stimulates a range of concerns among the responsible staff. If the intensive care unit staff are going to carry out the organ retrieval, they must rush in with demanding treatment measures such as defibrillation shock and cardiac massa...

This Note examines, in three parts, presumed consent laws as they pertain to organ donation. Part I discusses presumed consent and explains the salient features of presumed consent laws. It then discusses case law that addresses the aftermath of unauthorized organ or tissue harvesting. Part II evaluates the United States Supreme Court’s evolving conceptions of the rights of individual and famil...